Herbal Treatment for Paralysis
Neha Deokate, Sucheta Thombare, Amrata Mantri, Rajendra Patil
Delonix Society’s Baramati College of Pharmacy, Baramati.
*Corresponding Author E-mail: nehadeokate2@gmail.com
ABSTRACT:
Paralysis is when a person can not move or feel a part of their body. It happens when something goes wrong with the brain cells or nerves that control movement. It can be caused by inflammation, injuries, strokes, or diseases. A condition known as sleep paralysis (SP) refers to the immobility that sets in while a person is either sleeping or barely awake. It could manifest as isolated SP in healthy persons. Additionally, it has been linked to sleep, family, and other underlying psychiatric illnesses. According to the ratio, 8% of people in general have SP. Despite erroneous descriptions of this value, there is no accepted definition for the diagnosis of sleep paralysis. The literature now in publication describes SP for a number of reasons. One might see that these descriptions are either medically or culturally based. The disparity in SP diagnosis between medical professionals and members of cultural or ethnic groups has resulted in a variety of management strategies. The purpose of this review is to list medical. The exact method of action of stem cells is unknown. Objective: The aim of this study is to ascertain and contrast the prevalence, characteristics, neurological manifestation, and functional result of individuals suffering from nontraumatic spinal cord injury (SCI) with those suffering from traumatic SCI. 39% of SCI hospitalizations had a nontraumatic cause (tumor, 26%; spinal stenosis, 54%). Subjects with nontraumatic SCI were substantially (p <.01) older, more likely to be married, female, and retired than those with traumatic SCI. Within the nontraumatic SCI group, injury characteristics showed significantly higher rates of paraplegia and incomplete SCI (p <.01). From the time of admission to rehabilitation until the time of discharge, both nontraumatic and traumatic SCI patients experienced significant FIM changes (p <.01). Comparing the traumatic group to the nontraumatic SCI group, those with tetraplegia-incomplete group had significantly higher admission motor FIM scores and shorter rehabilitation duration of stay (p <.05). Compared to those with traumatic SCI, paraplegic-complete and paraplegic-incomplete nontraumatic SCI participants showed lower discharge motor FIM scores, FIM change, and FIM efficiency. Comparable rates of discharge to the home were observed in nontraumatic. This study aimed to examine the spinal cord injury experiences of younger and older individuals. Age at injury data from 866 hospitalized patients between 1973 and 1985 were examined. Results were assessed both two years following the injury and at discharge. Compared to patients aged 16 to 30, patients aged 61 or older had 2.1 times higher odds of developing pneumonia, 2.7 times higher odds of experiencing a gastrointestinal hemorrhage, 5.6 times higher odds of developing pulmonary emboli, and 16.8 times higher odds of having renal stones prior to first definitive discharge. In the second year following their accident, patients who were at least 61 years old had a 3.9-fold increased risk of being readmitted to the hospital.
INTRODUCTION:
What is paralysis?
Being unable to move your muscles voluntarily results in paralysis. Paralysis results from a Muscles receive messages from unharmed nerves. Muscles are activated by these impulses. There are portions of your body that you cannot move when you have paralysis. Inflammation on the nerves or any malfunction in the action of muscles causes paralysis.1
What are the degrees of severity of paralysis?
Some people experience temporary paralysis and regain partial or full movement over time. For example, Bell’s palsy temporarily paralyzes facial muscles. Palsy is the name for paralysis accompanied by tremors. Permanent paralysis means you never regain muscle control. The condition is irreversible. Paralysis can affect any part of the body. It can be:
· Partial (paresis): You can control some muscles, but not all.
· Complete: You have no control over any muscles.
Paralysis can also be broken down into two types based on the site of injury in the nervous system:
· Flaccid: Your muscles get flabby and shrink.
· Spastic: The muscles tighten, causing uncontrollable jerks and spasms.2
Fig. no. 1: paralysis ratio
Fig. No. 2: Age group in paralysis
Fig. no. 3: Type of paralysis
How is paralysis managed or treated?
Permanent paralysis has no known treatment. The spinal cord is not self-healing. Like Bell's palsy, temporary paralysis frequently disappears on its own with time if left untreated. It is not possible to treat paralysis permanently. In order to increase function, physical, occupational, and speech therapy can accommodate paralysis and offer exercises, medical gadgets, and adaptable environments. People with all kinds of paralysis can live more independently and have greater quality of life if their pain and swelling are under control.3
Mild signs and symptoms:
ache in the muscles that does not go away even after little exercise, twitches of muscle, ongoing vulnerability, tingling feeling extended periods of muscle weakness, jaw or ear pain on the afflicted side, diarrhea, bloating, clumsiness, numbness, feeling queasy or throwing up discomfort in the nape of the neck.
Severe signs and symptoms:
Drooling, having difficulty speaking, comprehending, recalling, or writing, or perusing, Bewilderment or unconsciousness, Alterations in mood, attitude, or behavior loss of auditory perception High temperature, loss of vision or changes to the visual system, intense headache, rashes, heightened sensitivity to hear, diminished ability to taste Face sagging and difficulty using the muscles in the face.8
How ayurvedic herbs helps in paralysis treatment:
Many plants and plant derivatives, such as ashwagandha powder and punarnava powder, are used in India to treat paralysis.
Other herbs for acute use may start to show results in one to three days. Body system tonification usually takes more time. Herbal tonics have a more gradual but profoundly helpful function that can be compared to long-term building. Usually, tonic herbs are used over an extended period of time—one month to three months or longer.3
For thousands of years, Ayurvedic herbs have been used to treat a wide range of illnesses, including paralysis. The goal of the Ayurvedic method is to heal the body by employing naturally occurring substances with therapeutic qualities. Which is safety in production. Ashwagandha, Shankhpushpi, Giloy, Jatamansi, and other Ayurvedic medicines are used to treat paralysis. These herbs aid in blood circulation improvement, inflammation reduction, and nerve restoration3,5,9
Fig. No. 4: Herbal Products
Ashwagandha:
Name in science: Withania somnifera
India has long practiced the traditional medicine known as ayurveda. Withania somnifera, which is commonly used in Ayurvedic medicine, is one of the most widely utilized plants. It is advantageous for a number of illnesses, including paralysis.
Ashwagandha’s potent physiological effects have earned it the moniker “Indian ginseng.” Being an adaptogen, this herb enhances the body’s ability to manage stress. Because of its ability to tonify and strengthen the neurological system, ashwagandha is also referred to as a “nerve tonic.” Ashwagandha is used in many different ways to alleviate paralysis. The herb is available as an extract, pill, or powder. It can also be prepared as a tincture or tea. Ashwagandha may aid in enhancing nerve3
Fig. no. 5: ashwagandha fruits
Fig. no. 6: Ashwagandha powder
Mechanism:
Fig. no 7: mechanism of action of ashwagandha
Fig. no. 8: Medical use of ashwagandha
Shankhpushpi:
Name according to science: Convolvulus prostrates:
Shankhpushpi is beneficial in reducing anxiety and tension by calming down brain activity. Because of its medicinal qualities, it also acts as a brain tonic, which enhances memory. Ayurvedic medicine frequently uses the medicinal plant sankhpushpi to treat a range of ailments, including paralysis. There are claims that the herb can effectively treat both transient and permanent paralysis.
Who is not supposed to eat Shankhpushpi?
Blood pressure-lowering medications: Shankhpushpi taken with these medications may have the potential to drop blood pressure, which could result in hypotension, or extremely low blood pressure. For people already using medications to decrease their blood pressure, this may cause dizziness.3
Fig no 9: Shankhpushpi flowers
Mechanism:
Fig. no. 10: mechanism of action
Giloy:
Name according to science: Tinospora Cordifolia:
Tinospora cordifolia, often known as giloy, has long been utilized in Ayurveda for its antioxidant and anti-inflammatory qualities. It can aid in enhancing nervous system activity and is particularly useful in the treatment of paralysis. Additionally recognized as an immune system enhancer, giloy is a perfect herb for paralyzed individuals who run the danger of contracting an infection. The stem of the giloy plant, which has a high nutritional content and alkaloids, is said to be very useful and effective. The leaves and roots may also be used to treat paralysis-related ailments. Giloy is a bitter-tasting plant. It aids in the treatment of a number of illnesses and is also utilized in the paralysis treatment.4,7
Fig. no. 11: Giloy branch
Fig. no. 12: giloy leaves and fruits
Jatamansi:
Scientific name: Nardostachys jatamansi:
Jatamansi is an herbal plant which has been used as ayurvedic medicine in various centuries. It is native to India and harvested in the Himalayan region. Jatamansi, also known as spikenard, has Been used in Ayurvedic medicine for its neuroprotective properties. It is traditionally used herbs. The roots and rhizomes of the plant are beneficial to use as Medicine. Jatamansi is effective on the nervous system and is often used to treat anxiety, stress, And insomnia. It is also used to treat various conditions such as seizures, paralysis, and Convulsions.3, 7
Fig. no. 13: Jatamansi flower
Fig. no. 14: Jatamansi roots
Vacha:
Name in science: Acorus calamus Linn:
The Indian plant vacha (Acorus Calamus) is used. It has been used for generations as an Ayurvedic herb to cure paralysis. Sweet flag, or vacha, is a herb that is frequently employed in Ayurvedic medicine due to its therapeutic and helpful qualities.
It has long been known to be useful in the treatment of paralysis because it enhances blood flow and lowers inflammation in the affected areas. The plant is used to cure a variety of ailments, including infections, sensitivities, and nerve diseases. It also helps to enhance blood circulation.3, 7
Fig no 15: Vacha flowers
Fig. no. 16: vacha plant
Brahmi herb:
Brahmi is a tiny, perennial herb with a long history of use for treating a wide range of illnesses. Acting as a nontoxic, brahmi just facilitates the body's ability to adjust to novel or challenging circumstances. It seems that brahmi has potent and highly powerful anti-inflammatory capabilities. It might strengthen your body's resistance against paralysis, when ingested, it raises serotonin levels in the brain, which promote mental clarity and provide relief from anxiety and paralysis. Brahmi herbs also aid in the treatment of impulsivity, restlessness, and hyperactivity condition.3, 7
Fig no 17: Brahmi herb powder
Fig no 18: Brahmi flowers
Turmeric Herb:
Another well-liked Ayurvedic treatment is the plant turmeric, an ancient Indian medicine with a variety of applications. The primary curcumin component possesses potent anti-inflammatory and antioxidant qualities. According to the results, it might be just as effective—if not more so—than some anti-inflammatory medications without any of the negative side effects.
There is a critical requirement for novel therapies utilizing turmeric to safeguard brain tissue following a stroke and enhance recuperation. Turmeric may help patients by promoting the growth of new cells. Turmeric contains compounds that increase brain cells, preserving brain function.6,7
Fig no 19: Turmeric oil
Fig. no. 20: Mechanism of action
CONCLUSION:
Effective and advantageous qualities of Ayurvedic medicine are applied to a comprehensive and holistic approach to treating paralysis, hence reducing symptoms associated with it. Ayurvedic doctors may also suggest chiropractic adjustments, massage therapy, acupuncture, and other therapies in addition to these herbal cures in order to assist the body regain its equilibrium, fight illness and paralytic disorders, and encourage healing. The five essential herbs are available now.
Strong antibacterial, analgesic, and anti-inflammatory qualities that are quite successful in lessening the intensity of paralysis symptoms.
When patients require individualized care, our practitioners blend traditional Ayurvedic treatments with the most recent medical expertise for your optimal health and wellbeing. Consult with as soon as possible to start on the path to improved health. Herbal medications have therapeutic benefits that are both safe and effective.5
Lavender Oil: Compounds like linalool, linalyl acetate, terpinen, and camphor are responsible for this attribute of lavender oil. Give the body all the nutrition it needs, with a focus on the muscles and ligaments. Reduces the patients’ experience of anxiety and sadness. helps the body heal by allowing the blood to unclog.
RESULT:
Tabel no. 1: % of paralysis in disease conditions
|
|
Gender Influence |
|
|||
|
Complication |
Patients |
Age Influence z |
Male (n = 32) |
Female (n = 38) |
x2+ |
|
Urinary Tract Infection |
46% (n = 32) |
-0.1, P = 0.9 |
38% |
53% |
1.6, P = 0.2 |
|
Pressure Ulcer |
37% (n = 26) |
-2.1, P = 0.04 |
34% |
39% |
0.2, P = 0.7 |
|
Pain |
23% (n = 16) |
0.8, P = 0.4 |
25% |
21% |
0.2, P = 0.7 |
|
Spasticity |
13% (n = 9) |
0.9, P = 0.4 |
16% |
11% |
0.4, P = 0.5 |
|
Pneumonia |
7% (n = 5) |
-0.4, P = 0.7 |
3% |
11% |
1.4, P = 0.2 |
|
Psychological |
7% (n = 5) |
0.05, P = 0.9 |
3% |
11% |
1.4, P = 0.2 |
|
DVT/PE |
3% (n = 2) |
0.1, P = 0.9 |
3% |
3% |
0.0, P = 0.9 |
Tabel no. 2: % of paralysis in workers
|
Job |
Total no. (2716) (%) |
Rural |
Urban |
||
|
Male (%) |
Female (%) |
Male (%) |
Female (%) |
||
|
Farmer |
23.2 |
86.1 |
8.1 |
5.5 |
0.3 |
|
Laboren |
22.9 |
79.1 |
2.9 |
17 |
1 |
|
House wife |
12.8 |
|
73.2 |
|
26.8 |
|
Business |
8.3 |
63.6 |
1.3 |
35.1 |
|
|
Student |
9 |
60.8 |
11.8 |
16.3 |
11.1 |
|
Clerical job |
5.5 |
68 |
1.3 |
30 |
0.7 |
|
Driver |
4.6 |
80 |
|
20 |
|
|
Mechanic |
2.4 |
75 |
|
25 |
|
|
Private job |
4.1 |
60 |
0.9 |
|
0.9 |
|
Teacher |
1.7 |
73.3 |
4.4 |
18.2 |
4.4 |
|
Electrician |
0.7 |
85 |
|
15 |
|
|
Not working |
3 |
56.6 |
14.5 |
19.3 |
9.6 |
|
Miscellaneous |
1.8 |
56.2 |
10.4 |
27.1 |
6.3 |
REFERENCE:
1. https://my.clevelandclinic.org/health/diseases/15345-paralysis
2. https://www.acko.com/health-insurance/diseases/paralysis/
3. https://saisanjivani.com/best-5-ayurvedic-herbs-for-paralysis-treatment/#:~:text=Ayurvedic%20herbs%20like%20Ashwagandha%2C%20Shankhpushpi,inflammation%2C%20and%20improve%20blood%20circulation
4. https://pharmeasy.in/blog/health-benefits-of-giloy-the-ultimate-immunity-booster/
5. https://www.nuayurveda.com/ayurvedic-treatments/facial-partial-sleep-half-body-paralysis-therapy-massage-patient-cure/amp/
6. https://www.hindawi.com/journals/nri/2016/9468193/
7. https://www.linkedin.com/pulse/paralysis-treatment-help-ayurveda-herbs-dr-nitesh-khonde
8. https://ijmrr.medresearch.in/index.php/ijmrr/article/download/605/1111/
9. https://www.ncbi.nlm.nih.gov/books/NBK92773/
10. https://www.medicalnewstoday.com/articles/herbal-medicine
11. https://www.sciencedirect.com/science/article/abs/pii/S0003999399901624
12. https://www.sciencedirect.com/science/article/abs/pii/S0003999301918519
13. https://pubmed.ncbi.nlm.nih.gov/2346397/
14. https://www.proquest.com/openview/33e7cb43acacd42c85cc4bd5c787d2c3/1?pq-origsite=gscholar&cbl=1819158
15. http://www.un.org/ageing/documents.htm
16. https://europepmc.org/article/med/934687
17. https://www.pmr.theclinics.com/article/S1047-9651(04)00069-5/abstract
18. https://www.sciencedirect.com/science/article/abs/pii/S0003999304002825
19. https://www.tandfonline.com/keyword/Age
20. https://www.tandfonline.com/doi/abs/10.1080/10790268.2001.11753581
21. https://www.sciencedirect.com/science/article/abs/pii/S0003999396902634
22. https://www.sciencedirect.com/science/article/abs/pii/S0003999300085555
23. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231844/
24. https://academic.oup.com/search-results?qb=%7b%22Keywords1%22:%22sleep+paralysis%22%7d
25. https://www.nuayurveda.com/ayurvedic-treatments/facial-partial-sleep-half-body-paralysis-therapy-massage-patient-cure/
26. https://images.app.goo.gl/P2dyzkrjJHj9YcCHA
27. https://www.researchgate.net/figure/A-Diagram-illustrating-the-paralysis-assay-showing-when-the-drug-was-administered-and_fig1_236072458
28. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369178/
29. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550454/ Sipski ML, Jackson AB, Gómez-Marín O, Estores I, Stein A. Effects of gender on neurologic and functional recovery after spinal cord injury. Arch Phys Med Rehabil. 2004; 85: 1826–1836.
30. Dijkers MP, Adela MB, Gans BM, Gordon WA. The aftermath of spinal cord injury. In: Stover S, DeLisa J, Whiteneck G, editors. Spinal Cord Injury: Clinical Outcomes from the Model Systems. Gaithersburg, MD: Aspen Publishers; 1995. Pp. 185–212
31. Kennedy P, Evans MJ, Berry C, Mullin J. Comparative analysis of goal achievement during rehabilitation for older and younger adults with spinal cord injury. Spinal Cord. 2003; 41: 44–52
32. Putzke JD, Barrett JJ, Richards JS, DeVivo MJ. Age and spinal cord injury: an emphasis on outcomes among the elderly. J Spinal Cord Med. 2003; 26: 37–44.
33. McKinley WO, Seel RT, Hardman JT. Nontraumatic spinal cord injury: incidence, epidemiology, and functional outcome. Arch Phys Med Rehabil. 1999; 80:619–623.
34. Scivoletto G, Morganti B, Ditunno P, Ditunno JF, Molinari M. Effects on age on spinal cord lesion patients’ rehabilitation. Spinal Cord. 2003; 41:457–464
35. Villanueva NE. Spinal cord injury in the elderly. Crit Care Nurs Clin North Am. 2000; 12: 509–519
36. Yarkony GM, Roth EJ, Heinemann AW, Lovell LL. Spinal cord injury rehabilitation outcome: the impact of age. J Clin Epidemiol. 1988; 41: 173–177
Received on 18.05.2024 Modified on 19.07.2024
Accepted on 23.08.2024 ©Asian Pharma Press All Right Reserved
Asian J. Pharm. Res. 2024; 14(3):341-346.
DOI: 10.52711/2231-5691.2024.00054